This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
- Generic Name
- Fluoride ion
- DrugBank Accession Number
- DB11257
- Background
Having a chemical formula of F−, fluoride ion is the simplest inorganic, monatomic anion of fluorine with basic properties. It is considered a trace element. Fluoride ions are found in various minerals but are only present in trace amounts in water. Its various salt forms and minerals play numerous roles as chemical reagents, industrial chemicals, and commercial products. It also plays an essential physiological role, such as enhancing the resistance profile and strength of the surface tooth enamel.
- Type
- Small Molecule
- Groups
- Approved
- Structure
- Weight
- Average: 18.9984
Monoisotopic: 18.998403205 - Chemical Formula
- F
- Synonyms
- Not Available
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Pharmacology
- Indication
Not Available
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- Associated Conditions
Indication Type Indication Combined Product Details Approval Level Age Group Patient Characteristics Dose Form Prophylaxis of Dental cavity •••••••••••• ••• Used in combination to prevent Hypovitaminosis d Combination Product in combination with: Cholecalciferol (DB00169) •••••••••••• •••••• •••••• - Contraindications & Blackbox Warnings
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- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
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- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available- Food Interactions
- No interactions found.
Products
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- Brand Name Prescription Products
Name Dosage Strength Route Labeller Marketing Start Marketing End Region Image Topex Neutral pH Fluoride Gel Mint Gel 9 mg/1g Dental Dentsply Llc. Professional Division Trading As "Sultan Healthcare" 1974-01-01 Not applicable Topex Neutral pH Fluoride Gel Strawberry Gel 9 mg/1g Dental Dentsply Llc. Professional Division Trading As "Sultan Healthcare" 1974-01-01 2023-08-18 - Mixture Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image D FLUORETTEN 500 Fluoride ion (0.25 mg/1) + Cholecalciferol (500 IU/1) Tablet 2006-07-01 Not applicable D FLUORETTEN 500 Fluoride ion (0.25 mg/1) + Cholecalciferol (500 IU/1) Tablet 2006-07-01 Not applicable ZYMAFLUOR D 1000 Fluoride ion (0.25 mg) + Cholecalciferol (1000 IU) Tablet 2006-07-01 Not applicable ZYMAFLUOR D 500 Fluoride ion (0.25 mg) + Cholecalciferol (500 IU) Tablet 2006-07-01 Not applicable ZYMAFLUOR D 500 Fluoride ion (0.25 mg) + Cholecalciferol (500 IU) Tablet 2006-07-01 Not applicable - Unapproved/Other Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image Multi-Vitamin Fluoride ion (1.0 mg/1) + Ascorbic acid (60 mg/1) + Cyanocobalamin (4.5 ug/1) + DL-alpha tocopheryl acetate (15 [iU]/1) + Folic acid (0.3 mg/1) + Niacin (13.5 mg/1) + Pyridoxine (1.05 mg/1) + Riboflavin (1.2 mg/1) + Thiamine chloride (1.05 mg/1) + Vitamin A (2500 [iU]/1) + Vitamin D (400 [iU]/1) Tablet, chewable Oral Boca Pharmacal, Inc. 2011-09-06 2014-12-31 Multi-Vitamin Fluoride ion (0.50 mg/1) + Ascorbic acid (60 mg/1) + Cyanocobalamin (4.5 ug/1) + DL-alpha tocopheryl acetate (15 [iU]/1) + Folic acid (0.3 mg/1) + Niacin (13.5 mg/1) + Pyridoxine (1.05 mg/1) + Riboflavin (1.2 mg/1) + Thiamine chloride (1.05 mg/1) + Vitamin A (2500 [iU]/1) + Vitamin D (400 [iU]/1) Tablet, chewable Oral Boca Pharmacal, Inc. 2011-12-28 2015-06-30 Multi-Vitamin Fluoride and Iron Drops Fluoride ion (0.25 mg/1mL) + Ascorbic acid (35 mg/1mL) + Cholecalciferol (400 [iU]/1mL) + Iron (10 mg/1mL) + Niacin (8 mg/1mL) + Pyridoxine (0.4 mg/1mL) + Riboflavin (0.6 mg/1mL) + Thiamine chloride (0.5 mg/1mL) + Vitamin A (1500 [iU]/1mL) + alpha-Tocopherol succinate (5 [iU]/1mL) Solution Oral Boca Pharmacal, Inc. 2011-04-20 2015-08-31 Multi-Vitamin Fluoride Drops Fluoride ion (0.25 mg/1mL) + Ascorbic acid (35 mg/1mL) + Cholecalciferol (400 [iU]/1mL) + Cyanocobalamin (2 ug/1mL) + Niacin (8 mg/1mL) + Pyridoxine (0.4 mg/1mL) + Riboflavin (0.6 mg/1mL) + Thiamine chloride (0.5 mg/1mL) + Vitamin A (1500 [iU]/1mL) + alpha-Tocopherol succinate (5 [iU]/1mL) Solution Oral H.J. Harkins Company 2011-05-04 Not applicable Multi-Vitamin Fluoride Drops Fluoride ion (0.5 mg/1mL) + Ascorbic acid (35 mg/1mL) + Cholecalciferol (400 [iU]/1mL) + Cyanocobalamin (2 ug/1mL) + Niacin (8 mg/1mL) + Pyridoxine (0.4 mg/1mL) + Riboflavin (0.6 mg/1mL) + Thiamine chloride (0.5 mg/1mL) + Vitamin A (1500 [iU]/1mL) + alpha-Tocopherol succinate (5 [iU]/1mL) Solution Oral Boca Pharmacal, Inc. 2011-06-06 2015-08-31
Categories
- Drug Categories
Not Available
- Chemical TaxonomyProvided by Classyfire
- Description
- This compound belongs to the class of inorganic compounds known as hom*ogeneous halogens. These are inorganic non-metallic compounds in which the largest atom is a nobel gas.
- Kingdom
- Inorganic compounds
- Super Class
- hom*ogeneous non-metal compounds
- Class
- hom*ogeneous halogens
- Sub Class
- Not Available
- Direct Parent
- hom*ogeneous halogens
- Alternative Parents
- Not Available
- Substituents
- hom*ogeneous halogen
- Molecular Framework
- Not Available
- External Descriptors
- halide anion, monoatomic fluorine (CHEBI:17051) / an anion (F-)
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- Q80VPU408O
- CAS number
- 16984-48-8
- InChI Key
- KRHYYFGTRYWZRS-UHFFFAOYSA-M
- InChI
InChI=1S/FH/h1H/p-1
- IUPAC Name
fluoride
- SMILES
[F-]
References
- General References
- Not Available
- External Links
- PDB Entries
- 1bs3 / 1e6a / 1lh5 / 1nel / 1t5g / 2akz / 2au6 / 2au9 / 2auu / 2dqz … show 83 more
Clinical Trials
- Clinical Trials
Phase Status Purpose Conditions Count
Pharmacoeconomics
- Manufacturers
Not Available
- Packagers
Not Available
- Dosage Forms
Form Route Strength Injection, solution, concentrate Intravenous Tablet Tablet, chewable Oral Solution Oral Suspension / drops Oral Gel Dental 9 mg/1g Gel - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source logP 0.15 Chemaxon pKa (Strongest Acidic) 3.17 Chemaxon Physiological Charge -1 Chemaxon Hydrogen Acceptor Count 0 Chemaxon Hydrogen Donor Count 0 Chemaxon Polar Surface Area 0 Å2 Chemaxon Rotatable Bond Count 0 Chemaxon Refractivity 0.87 m3·mol-1 Chemaxon Polarizability 0.44 Å3 Chemaxon Number of Rings 0 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule Yes Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Not Available
- Chromatographic Properties
Collision Cross Sections (CCS)
Adduct CCS Value (Å2) Source type Source [M-H]- 108.0462 predicted
DeepCCS 1.0 (2019) [M-H]- 108.0462 predicted
DeepCCS 1.0 (2019) [M+H]+ 109.7789 predicted
DeepCCS 1.0 (2019) [M+H]+ 109.7789 predicted
DeepCCS 1.0 (2019) [M+Na]+ 116.56366 predicted
DeepCCS 1.0 (2019) [M+Na]+ 116.56366 predicted
DeepCCS 1.0 (2019)
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Learn moreDrug created at December 03, 2015 16:51 / Updated at June 12, 2020 16:53